Brandon Johnson, MD - full bio

Dr. Johnson has expertise in all areas of retinal surgery including macular holes, macular pucker, retinal detachment, and diabetic vitrectomy.

Dr. Brandon Johnson is an Assistant Professor of Ophthalmology at the Icahn School of Medicine at Mount Sinai School of Medicine. Dr. Johnson graduated Magna Cum Laude from Haverford College and received his Doctor of Medicine degree from the University of Pennsylvania Perelman School of Medicine where he received an award for outstanding medical student research. Dr. Johnson completed his internship in General Surgery at the Hospital of the University of Pennsylvania. He performed his ophthalmology residency at the Wills Eye Institute at Thomas Jefferson University. Dr. Johnson completed his two-year vitreoretinal surgery fellowship at Emory University.

Dr. Johnson is Board Certified by the American Academy of Ophthalmology. Dr. Johnson has authored numerous articles and book chapters on vitreoretinal diseases and has lectured at ophthalmology meetings. Dr. Johnson enjoys actively participating in the training of ophthalmology residents.

He has been involved as a clinical investigator in several clinical trials pertaining to age-related macular degeneration, diabetic retinopathy, retinal vein occlusions, uveitis, and vitreoretinal surgery. Dr. Johnson is a member of the American Academy of Ophthalmology, American Society of Retina Specialists, Association for Research in Vision and Ophthalmology, and American Medical Association.

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Case Reports in Ophthalmological Medicine
Traumatic Submacular Hemorrhage with Macular Hole Repaired by Pneumatic Displacement and Intravitreal t-PA Injection

A 27-year-old male with no past medical history presented to the Emergency Department after sustaining blunt trauma to his right eye secondary to an airbag injury. Visual acuity measured 20/400 in the affected eye. Funduscopic examination demonstrated an arcuate choroidal rupture inferior to the optic nerve and subretinal hemorrhage extending from the optic nerve into the fovea.

Complications of ocular trauma include subretinal hemorrhage, macular hole, CNV, retinal detachment, and other potentially sight-threatening conditions. SMH is a potential visually devastating condition, most commonly associated with CNV due to AMD [1, 5, 6]. Subretinal blood and blood products damage retinal tissues through the toxic effects of iron, hemosiderin, and brin on the overlying photoreceptors. In addition, clot retraction can sheer and damage the photoreceptors while the physical separation of the photoreceptors from the RPE can lead to profound reti- nal dysfunction [1, 2, 5]. Management of SMH has been described using multiple approaches alone or in combination with varying success including observation, PPV, pneumatic displacement, t-PA, and anti-VEGF [4–6].

Retinal Hemangioblastoma and Syrinx in von Hippel–Lindau Disease

A 14-year-old boy presented with decreased vision in his left eye for 4 weeks. Review of systems was otherwise negative.

Best-corrected visual acuity was 20/20 on the right eye and 20/100 on the left eye. Ophthalmoscopy of the right eye revealed a normal fundus and optic nerve; evaluation of the left eye revealed an exudative retinal detachment with a macular star. A reddish-orange vascular tumor emanated from the tortuous superior arcade of the left eye. The inferotemporal retina contained 3 smaller lesions with associated exudation. Magnetic resonance imaging revealed several enhancing spinal cord nodules and a cervical spine syrinx. Spectral domain optical coherence tomography of the macula showed macular exudation and retinal detachment. Von Hippel–Lindau disease can present with profound visual disturbance secondary to macular exudation and retinal detachment because of retinal hemangioblastoma.

Distinctive White Fundus Lesions In Familial Exudative Vitreoretinopathy: A Newly Characterized Clinical Feature

Purpose: To report a novel clinical finding associated with familial exudative vitreoretinopathy in three patients using fundus photography, fluorescein angiography, and histopathology.

Methods: Observational case series of three patients with familial exudative vitreoretinopathy, an ophthalmic examination with fundus photography, and fluorescein angiography were used to document clinical findings between January 2007 and January 2015. Surgical specimens from one case were examined using standard histopathologic techniques, as well as transmission electron microscopy and energy dispersive x-ray analysis.

Results: Distinctive white preretinal granules were noted in all cases and were found to be extramacular in location. Histopathology in one case revealed the granules to be crystalline structures with a regular pattern evident on higher magnification. The chemical constitution was found to be carbon, oxygen, and fluorine.

Conclusion: Our case series represents the first description of white preretinal granules in association with familial exudative vitreoretinopathy. The authors have not seen these granules in other forms of retinopathy and their presence may aid in differentiating this disease from other entities.

RETINA, The Journal of Retinal and Vitreous Diseases
Diagnostic and Therapeutic Challenges

This case is submitted by Drs. Jing G. Wang and Brandon Johnson of the Department of Ophthalmology, Bronx-Lebanon Hospital Center, Bronx, New York; commented by Dr. Lucia Sobrin.

A 10-year-old Hispanic boy presented with painless vision loss in the right eye for 1 month. There was no significant medical or birth history except a hospitalization for pneumonia as an infant. The family moved from the Dominican Republic 4 months before presentation. Family history was unremarkable except for an 11-year-old cousin with an undiagnosed eye problem.

His best-corrected visual acuity was 20/150 in the right and 20/70 in the left eye. Intraocular pressure and pupillary examination were within normal limits. The anterior segment examination was normal, and there were no signs of inflammation in the vitreous.

Frontal Sinus Mucocele Diagnosed by Fundus Examination and B-Mode Ultrasonography

This case report discusses the evacuation of a frontal sinus mucocele via craniotomy in an adult man seen in the emergency department with pain over his left eye for several days.

A man in his 40s was seen in our emergency department with pain over his left eye for several days. He had a remote history of trauma with skull fracture 14 years previously. External examination showed left hypoglobus and limitation of upgaze, and dilated fundus examination demonstrated choroidal folds in the left eye (Figure, A). B-mode ultrasonography showed a hypoechoic pseudocystic orbital lesion causing globe deformity. Magnetic resonance imaging confirmed the diagnosis of frontal sinus mucocele and revealed intracranial extension with left frontal lobe enhancement representing encephalomalacia (Figure, B). The patient underwent evacuation of the mucocele through a frontal craniotomy approach and had postoperative resolution of hypoglobus and choroidal folds.

Book Chapter "Amblyopia and Strabismus" - American Academy of Pediatrics. Textbook of Pediatric Care.

For more than 75 years, the American Academy of Pediatrics has been the nation’s leading and most trusted child health expert. The all-new full color AAP Textbook continues the tradition by providing a wealth of expert guidance spanning every aspect of current clinical practice and sets a new standard for one-stop pediatric references! Directed by a distinguished editorial team, and featuring contributions from experienced clinicians nationwide, the new AAP Textbook of Pediatric Care is a resource you’ll use with complete confidence. Look here for expert guidance spanning every aspect of current clinical practice.

Book Chapter “Retina” - The Wills Eye Manual: Office and Emergency Room Diagnosis and Treatment of Eye Disease

"The goal of the book has always been to provide a quick reference containing concise answers to diagnostic and therapeutic problems that span most of ophthalmology. The Wills Manual provides essential diagnostic tips and specific therapeutic information pertaining to eye disease. These are the issues that the ophthalmology resident, the attending ophthalmologist and the emergency room physician must deal with on a daily basis"

Book Chapter “Weill-Marchesani.” and “Amaurosis Fugax.” - Wills Eye Institute 5-Minute Ophthalmology Consult

The Wills Eye Institute 5-Minute Ophthalmology Consult provides a readily accessible and focused compendium of ophthalmic abnormalities that will be useful for students, physicians and ancillary medical staff. Evidence-based references are included and algorithmic flow diagrams are provided for rapid problem solving. In keeping with the very successful 5-Minute Clinical Consult brand, over 330 topics will be covered, each in a highly formatted 2-page spread.

Vitreous Hemorrhage

Vitreous Hemorrhage is a relatively common cause of acute vision loss, having an incidence of approximately 7 cases per 100,000[1]. It is therefore frequently encountered by ophthalmologists and Emergency Room professionals alike. Although the diagnosis of vitreous hemorrhage is often straightforward to make on fundoscopic examination or ultrasonography, further investigation may be required to determine the underlying etiology.

"Wills Eye Resident Case Series: MALT lymphoma"

A 50-year-old male with no past ocular history presented to the Wills Eye Emergency Room with pain and foreign body sensation in his right eye. The patient works as a firefighter and had a shattered-glass injury to his eye while at work two days prior to presentation. He was found to have several small pieces of glass on his right eyelid and superficial cornea that were removed at the slit lamp. He was treated with Bacitracin/Polymixin ointment and instructed to return to the Wills Eye Cataract and Primary Eye Care clinic in one week. During his follow-up evaluation, the patient noted marked improvement of his symptoms.